Millions of children receive anesthesia each year. Non‐clinical studies in juvenile animal models show that exposure to some anesthetics and sedatives is associated with memory and learning deficits and other neurodegenerative changes in the central nervous system. Insufficient human data exist to support or refute the possibility that similar effects occur in children.
To address the critical public health issues associated with the safe use of anesthesia and sedatives in young children, the International Anesthesia Research Society (IARS) partnered with the US Food and Drug Administration, and is working with multiple stakeholders (e.g. professional societies, academic research institutions, patient advocacy groups, industry and other government and nonprofit organizations), to address scientific and clinical gaps regarding the safe use of anesthetics and sedatives in children.
SmartTots is a multi‐year collaborative effort designed to increase the safety of anesthetic drugs for the millions of infants and children who undergo anesthesia each year. Research funded through SmartTots investigates multiple aspects of existing anesthetics and their administration, including dosage and exposure. Findings from these studies will establish the development of new practice guidelines and anesthetic drugs. Data, outcomes and best practices generated by SmartTots will be placed in the public domain.
100% of all charitable donations to SmartTots go directly to fund research.
SmartTots has released a Consensus Statement regarding the safety of anesthetics and sedative agents administered to infants and young children which is endorsed by the IARS, AAP, FDA, SPA, SNACC, ESA and the ASA.
About the IARS
The IARS is anesthesiology's non-political organization focused on providing scientific and evidence-based safe anesthesia care. Founded in 1922, the IARS contributes more than $1 million annually to fund anesthesia research and provides a forum for leaders in anesthesia research to share information and ideas. Membership includes physicians and others engaged in anesthesia-related practice, research, and training worldwide.
The IARS mission is to encourage, stimulate and fund ongoing anesthesia-related research projects that will enhance and advance the specialty and to disseminate current, state-of-the-art, basic and clinical research data in all areas of clinical anesthesia, including perioperative medicine, critical care, and pain management. The IARS is focused solely on the advancement and support of education and scientific research related to anesthesiology.
To fulfill this mission, the Society publishes the monthly scientific journal, Anesthesia & Analgesia, conducts an annual clinical and scientific meeting, funds anesthesia-related research, and sponsors the SmartTots research initiative.
IARS Annual ReportFY2010 Annual Report
FY2011 Annual Report