N Engl J Med, February 2015.
Rappaport BA, Suresh S, Hertz S, Evers AS, Orser BA
Abstract
Some anesthetics and sedatives have been shown to cause neurotoxic effects in laboratory animals. The FDA collaboration SmartTots recommends undertaking large-scale clinical studies and avoiding nonurgent surgical procedures requiring anesthesia in children younger than 3 years of age.
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